Contact an Account ManagerSeparation of ramipril optical isomers by HPLC
Summary
Type: HPLC
Application #: 104060
Catalog#: 720093.46 - MN HPLC Column, Nucleosil, 50A, 5um, 4.6x250mm
Detection: left: UV, 254nm
right: UV, 210nm
Conditions: left: ; eluent: hexane - tetrahydrofuran (4:1), flow rate 2ml/min
right: ; eluent: 0.15% KH2PO4 pH 3.0 with H3PO4 - acetonitrile (1:2), flow rate 1ml/min
Authors: Ito M
Source: J Liquid Chromatogr 13 (1990) 991 - 1000
Details
Legend: Left: Fig. 3. Chromatogram of precursor I and its optical isomers derivatized
with (-)-1-(1-anthryl)ethylamine.
Right: Fig. 7. Chromatogram of ramipril and its optical isomer (RS-SSS).